Abstract
In hemodialysis patients, blood pressure (BP) measured at the postdialysis period (POSBP) can be used to diagnose hypertension. However, the optimal time point for POSBP remains uncertain. This cross-sectional study evaluated 210 long-term dialysis patients (66.7% men; age = 56.9 ± 15.7 years), who underwent POSBP measurements at three time points [immediately after dialysis period ended (POSBP1); after blood return (POSBP2) and after fistula hemostasis or catheter sealing (POSBP3)] and home BP monitoring (HBPM) over one week. POSBP1, POSBP2, POSBP3 and HBPM values were 139.1 ± 22.4/73.2 ± 12.5, 142.8 ± 22.8/74.3 ± 12.3, 142.8 ± 21.8/74.0 ± 12.2 and 131.2 ± 21.2/77.9 ± 12.1 mmHg, respectively. Systolic POSBP3 and POSBP2 were significantly greater (p < 0.05) than systolic POSBP1. POSBP3 had the greatest correlation with HBPM, while elevated (>130/80 mmHg) POSBP3 showed the highest numerical accuracy (AUC [95% CI] = 0.696 [0.638–0.754]) and concordance (kappa coefficient = 0.41) with elevated HBPM (≥130/80 mmHg) compared with POSBP1 and POSBP2. These findings suggest that POSBP3 may be a preferable measurement for assessment of POSBP in hemodialysis patients.

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Funding
The study was supported by the Brazilian National Council for Scientific and Technological Development (CNPq; grant 310869/2021-8 for Dr. Nadruz).
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Bezerra, R., Gorayeb-Polacchini, F.S., Teles, F. et al. Optimal timing for post-dialysis blood pressure measurement: relationship with home blood pressure monitoring. Hypertens Res 48, 1169–1173 (2025). https://doi.org/10.1038/s41440-025-02103-4
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DOI: https://doi.org/10.1038/s41440-025-02103-4
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