Fig. 1

DCE-MRI was performed using injection of contrast media (Gd-DTPA) and aquring serial images in order to measure blood perfusion.DCE-MRI Ktrans map is calculated from the serial images (see S-1 for further details). a Penile MRI coordinates of measurement. T2 MRI sequence demonstrates the 4 locations in each CC which were used to extract K-trans values. The base of the penis area was chosen for better localization in each patient and variability reduction. b Average MRI dynamic contrast enhancement (DCE) maps pre and post HBOT. Black to blue and green (in this order) reflect low K-trans values = low perfusion in the corporoa cavernousa. Yellow and red (in this order) reflect high K-trans values = increased perfusion in the corpora cavernousa. Top row: K-trans values at baseline. Middle row: K-trans values after HBOT. Bottom row: delta map showing increase in K-trans after HBOT