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A nationwide multicentric analysis of lengthening corporoplasty with collagene fleece in Peyronie’s disease

International Journal of Impotence Research (2025)Cite this article

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Abstract

Lengthening corporoplasty is recommended for Peyronie’s disease (PD) patients with severe (>60°) or complex curvature and preserved erectile function. This study aimed to evaluate lengthening corporoplasty outcomes using a graft of collagen fleece in Portugal. A multicentric retrospective study included PD patients who underwent the procedure between 2016 and 2024 at four Portuguese hospitals. Among 88 patients, the median age (IQR) was 59.0 (56.0–63.0) years, International Index of Erectile Function-5 (IIEF-5) score 22.5 (22.0–23.0), stretched penile length (SPL) 13.0 (12.0–14.0) cm, and curvature angle 80.0° (78.8–90.0)°. Dorsal curvature was most common (65.9%) and the median surgery duration was 92.5 (80.0–106.3) min. Early postoperative hematoma occurred in 8.0% of cases, and 2.3% had surgical site infections. No surgical reinterventions were needed. After a median follow-up of 31 months, complications included erectile dysfunction (38.6%), residual curvature (19.3%), reduced penile length (9.1%), penile pain (8.0%), and glans hypoesthesia (5.7%). SPL was 13.8 (12.5–15.0) cm immediately postoperative and 14.0 (13.0-15.0) at 1 month. New-onset erectile dysfunction treatments included phosphodiesterase type 5 inhibitors (34.1%), intracavernous alprostadil (1.1%), and penile prosthesis (3.4%). This study demonstrates effective curvature correction but high rates of postoperative erectile dysfunction, often requiring treatment.

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Fig. 1: Summary of lengthening corporoplasty with TachoSil®.

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Data availability

The data used to support the findings of this study are restricted by the Ethics Commission in order to protect patient privacy. The data used to support the findings of this study are available from the corresponding author upon request and approval by local ethical commission.

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Author information

Authors and Affiliations

  1. Centro Hospitalar Universitário São João, Porto, Portugal

    Alberto Costa Silva, Simone Cilio & Afonso Morgado

  2. Faculdade de Medicina da Universidade do Porto, Porto, Portugal

    Alberto Costa Silva, Simone Cilio & Afonso Morgado

  3. U.O.C. Clinica Urologica, A.O.U. San Giovanni di Dio e Ruggi d’Aragona “Scuola Medica Salernitana”, Salerno, Italy

    Simone Cilio

  4. Unidade Local de Saúde Santa Maria, Lisboa, Portugal

    André Ye & Pedro Oliveira

  5. Unidade Local de Saúde de Santo António, Porto, Portugal

    Nuno Vinagre, André Marques-Pinto & Nuno Louro

  6. Hospital da Luz Arrábida, Porto, Portugal

    Nuno Tomada

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  1. Alberto Costa Silva
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Contributions

Study design: ACS, AMP, NL, PO, AM, NT; Data collection: ACS, SC, AY, NV, NT; Manuscript revision: ACS, SC, AY, NV, AMP, NL, PO, AM, NT.

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Correspondence to Alberto Costa Silva.

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The authors declare no competing interests.

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Informed, written consent has been obtained. The study was approved by the local ethics committee of University Hospital Center of São João with authorization number 90/22 and is according to the Declaration of Helsinki.

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Costa Silva, A., Cilio, S., Ye, A. et al. A nationwide multicentric analysis of lengthening corporoplasty with collagene fleece in Peyronie’s disease. Int J Impot Res (2025). https://doi.org/10.1038/s41443-025-01036-3

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