Figure 1 | Nature Communications

Figure 1

From: Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer

Figure 1

Reactions catalyzed by the malonate decarboxylase (MDC) system. a Chemical structure of the 2′-(5′′-phosphoribosyl)-3′-dephospho-CoA prosthetic group for the acyl-carrier protein (MdcC) in malonate decarboxylase. b Malonate decarboxylase contains two distinct active sites. MdcA is an acetyl-ACP:malonate ACP transferase and converts free malonate to malonyl-ACP, which is then decarboxylated by MdcD–MdcE. The prosthetic group of the MdcC is indicated with the wavy lines. MdcB, MdcG and MdcH are involved in activating the ACP for catalysis (shown in gray)

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