Fig. 1 | Nature Communications

Fig. 1

From: Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

Fig. 1

Sample origin and processing. a Traditional iliac crest specimens (random aspirates) and CT-guided fine needle aspirates were enriched for malignant plasma cells using CD138-positive selection. Mutational and chromosomal profiles were investigated using whole-exome sequencing and high-resolution copy number arrays. b Disease state at sampling, treatment history, the total number of focal lesions in medical imaging, and the number and type of investigated samples are depicted. c Origin and number of samples. FL focal lesion, FNAS fine needle aspirate, RNAS random aspirate, EMD extramedullary disease, auto SCT autologous stem cell transplantation

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