Table 1 Characterization of PACE polymers

From: Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells

Name

PDL:DES:MDEA (feed molar ratio)

PDL:DES:MDEA (molar ratio, NMR)

M W

M W/M n

Nitrogen content (wt%)

PACE-50

50:50:50

54:46:46

37,586

2.5

2.7

PACE-60

60:40:40

62:38:38

46,811

3.3

2.2

PACE-70

70:30:30

72:28:28

31,569

1.9

1.6

PACE-80

80:20:20

82:18:18

35,400

2.2

1.0

PACE-90

90:10:10

91:9:9

41,500

2.1

0.6

  1. Polymers were synthesized using 50 to 90% PDL. % PDL was calculated based on PDL feed molar ratio (PDL:PDL + DES). PDL:DES:MDEA molar ratios in the resulting polymers were measured using NMR and polymer molecular weight was measured using GPC
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