Fig. 9 | Nature Communications

Fig. 9

From: Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion

Fig. 9

The metastasis promoting effect of CLDN4 could be regulated in vivo. a, b Transverse section of 18F-FDG PET images of mice at the 56 day after tail vein injection with 1 × 106 SGC-7901 cell clones and the max SUVs were analyzed in each group. Data are mean ± s.d. of the tumor volumes, n = 8, *P < 0.05. c The gross lesion of lung tissues isolated from the mice. d The microscopic images of lung tissue sections stained by hematoxylin and eosin. Scale bars = 500μm. e The number of metastatic nodules in the lungs from 56 days after tail vein injection in a (five sections evaluated per lung). Data are mean ± s.d. of the tumor volumes, n = 8, *P < 0.05. f, g Transverse section of 18F-FDG PET images of mice at the 56 day after tail vein injection with 1 × 106 HGC-27 cell clones and the max SUVs were analyzed in each group. Data are shown as mean ± s.d. of the tumor volumes, n = 8. The data statistical significance is assessed by Student’s t-test. *P < 0.05

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