Fig. 2
From: Poliovirus intrahost evolution is required to overcome tissue-specific innate immune responses
The tissue distribution of the virus strains in Tg21 and IFNAR−/− mice. a Experimental schematic for determining the virus titer in individual tissues. b, c Virus titers in tissue collected from WT or GD infected mice by I.P. inoculation route. Tg21 (106 PFU per mouse) or IFNAR−/− (104 PFU per mouse). Data are shown as logarithm, mean ± s.d., PFU per gram of tissue (n = 5, the number of mice is five for each time point and each group). Student’s t-test, n.s. indicates P > 0.05, *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001. Limited detection level is 20 PFU per gram tissue
