Fig. 3
From: CLEC5A is a critical receptor in innate immunity against Listeria infection
CLEC5A is critical for restriction of bacterial spreading in vivo. a, b Wild type (WT), WT/DNase-I (4 KU per mouse) and mutant mice were injected with the live luminescent L. monocytogenes (Xen32) (3 × 108 CFUs per mouse) intravenously, and luminescence intensity in liver was determined at 1 h, 2 h, and 4 h post- infection (10 mice per group) by IVIS system (Xenogen). Bacterial loads in liver c and blood d were determined 4 h post-infection. The data were collected and expressed as mean ± s.e.m. from four independent experiments (n = 20). One-way ANOVA test performed. *P < 0.05, **P < 0.01, ***P < 0.001 for WT versus mutant mice, WT versus WT/DNase-I mice or indicated two groups
