Fig. 3

Importance for elevated blood pressure during whole body physical activity. Telemetry measurements of mean, systolic and diastolic blood pressures in conscious freely moving control (n = 6) and Piezo1ΔEC (n = 7) mice. Data were analysed when the mice were inactive during the day a and voluntarily active on a running wheel during the night b. Time zero is when the mouse was introduced to the running wheel cage. Measurements were not made during the first 2 days of acclimatization. Averaged data are displayed as mean ± s.e.m. Data sets are compared by t-test. Statistical significance is indicated by *P < 0.05, **P < 0.01, ***P < 0.001