Fig. 5
Kaplan–Meier plot for overall survival (OS) by A3A and A3B expression and genotype in OSCC-Taiwan and OSCC-TCGA. a Kaplan–Meier plot showing that the 10-year OS rates for patient subgroups stratified by high vs. low A3A expression were 85.1% and 65.9%, respectively (p = 0.004) in the OSCC-Taiwan data set, whereas no significant difference was found in the OSCC-TCGA data set (p = 0.239). b No significant difference in OS was found for subgroups stratified according to A3B expression (right) in the OSCC-Taiwan and OSCC-TCGA datasets. c Kaplan–Meier plot for OS in subgroups stratified by A3A expression among the 143 patients in the OSCC-Taiwan data set. High A3A in patients with the A3B +/− (n = 89) and A3B −/− (n = 27) genotypes, but not the A3B +/+ (n = 27) genotype, was significantly correlated with better OS. d Kaplan–Meier plot for OS in subgroups stratified by A3A expression among the 312 patients in the OSCC-TCGA data set. No significant correlation was found in patients with the A3B +/+ (n = 278) or A3B +/− (n = 34) genotypes. The y-axis shows the probability of OS according to high and low A3A expression. The survival rate was estimated by Kaplan–Meier plotting and compared by log-rank test; all p-values are two-sided, with the significance level set at p < 0.05
