Table 1 Population characteristics at MESA Exam 5

From: Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Characteristicsa

Overall (N = 1208)

By site

  

Study 1 (JHU + CO) (N = 709)

Study 2 (UMN + WFU) (N = 499)

Demographic

 Age (years)

70 ± 9

70 ± 9

69 ± 9

 Sex (% female)

51.4

55.0

46.3

Race/ethnicity

 African American (%)

21.5

36.1

0.8

 Hispanic (%)

32.6

29.3

37.3

 Caucasian (%)

45.9

34.6

61.9

Cigarette smoking

 Former (%)

51.7

49.1

55.5

 Current (%)

9.1

8.1

10.5

Clinical and laboratory

 BMI, (kg m−2)

30 ± 6

30 ± 6

30 ± 5

 LDL-C (mg dl−1)

105 ± 32

107 ± 33

102 ± 30

 HDL-C (mg dl−1)

54 ± 16

57 ± 17

50 ± 13

 Impaired glucose tolerance (%)

45.6

44.3

47.5

 Diabetes (%)

23.0

25.2

19.8

 Hypertension (%)

60.9

63.8

56.6

 Carotid plaque score, median (IQR)

2 (0–4)

2 (0–3)

2 (0–4)

 Coronary artery calcium score, median (IQR)

46 (0–305)

32 (0–227)

76 (0–397)

 Prevalent CVD (%)

5.3

4.2

6.8

 Statin use (%)

38.5

35.7

42.5

  1. BMI body mass index, CO Columbia University, CVD cardiovascular disease, HDL-C high-density lipoprotein-cholesterol, IQR interquartile range, JHU John Hopkins University, LDL-C low-density lipoprotein-cholesterol, UMN University of Minnesota, WFU Wake Forest University
  2. aPlus-minus values are means ± SD