Fig. 1
From: Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
Membrane proteome analysis of undifferentiated hESCs and day 13 differentiated PP and PH cultures. a Schematic representation of the four stages of differentiation from human embryonic stem cells (hESCs) to pancreatic progenitor (PP) or polyhormonal (PH) cells. b Workflow of the strategy used for enriching N-linked glycosylated peptides for liquid chromatography—mass spectrometry. c Heatmap showing the 2222 identified deglycosylated sites, grouped into 11 clusters. Pearson correlation distances at the top show the relationship within the biological replicates, and between the different sample types. d Line graphs showing the intensity profiles of deglycosylated sites for the first six clusters. The bold line represents the mean intensity profile of all the deglycosylated sites in the respective cluster
