Table 1 Distribution of fusion types in patients and cell lines. Recurrent fusions are defined as those occurring in at least two samples in the same population, and percentages are given in terms of percentages of different pairs of partner genes (unique fusions). More than 80% of fusions are specific to one cell line, but only 64% of fusions found in patients are patient-specific. Among unique fusions, more than half are same-chromosomes and less than 10 million bases apart, suggesting read-through fusions, deletions or in situ amplifications
From: Expressed fusion gene landscape and its impact in multiple myeloma
IFM | Cell lines | |
---|---|---|
Ig fusions | 36% | 17.7% |
Recurrent fusions | 28.8% | 11.6% |
Recurrent non-Ig fusions | 17.2% | 7.1% |
Others | 46.9% | 75.2% |
Other—same chr | 54.2% | 66.6% |