Table 2 Percentage of individuals with identified Ig fusion transcripts in different groups. Almost half of the cohort have at least one Ig fusion, almost 60% in cell lines. There are a large number of fusions involving Kappa (79 patients, all but one have kappa phenotype). Fusions involving Lambda are surprisingly rare, even in the Lambda phenotype patients

From: Expressed fusion gene landscape and its impact in multiple myeloma

 

All IFM

IgK patients

IgL patients

Cell lines

Ig fusions

47.3%

49%

42.6%

59.1%

IgH fusions

22.7%

18.2%

29.4%

40.8%

IgK fusions

31%

47.8%

1.5%

21.1%

IgL fusions

4.3%

0%

14.5%

8.4%