Fig. 6

Effects of Oxtr deletion on morphological features and excitatory synaptic transmission of mature DGCs. a Representative micrographs of biocytin-filled mature DGCs from WT and Oxtr ^−/− mice. Scale bar, 50 μm. b, c Summary bar graphs depicting b the total dendritic length and c branch number of mature DGCs from WT and Oxtr ^−/− mice (n = 8 neurons from 5 mice per genotype; unpaired two-tailed Student’s t test). d Sholl analysis of dendritic complexity of mature DGCs from WT and Oxtr ^−/− mice (n = 8 neurons from 5 mice per genotype, two-way ANOVA). e Representative traces of mEPSCs recorded from mature DGCs in slices from WT and Oxtr ^−/− mice. f, g Cumulative probability plots of mEPSC f interevent intervals and g amplitude (n = 5 neurons from 3 mice per genotype, Kolmogorov-Smirnov test) in mature DGCs from WT and Oxtr ^−/− mice. h, i Summary bar graphs depicting the averaged h frequency and i amplitude of mEPSCs in mature DGCs from WT and Oxtr ^−/− mice (n = 5 neurons from 3 mice per genotype; *P < 0.05, unpaired two-tailed Student’s t test). Data represent the mean ± s.e.m