Fig. 4

15N–13Cα solid-state NMR spectra of PrP23-144 fibrils generated at 25 °C under quiescent conditions and at 37 °C with rotation. Assigned two-dimensional 15N–13Cα fingerprint solid-state NMR spectra are shown for q25 (blue contours) and r37 (red contours) amyloid fibrils as indicated in the insets for a hu, b hu I138M, c mo, and d Sha PrP23-144