Table 3 Coding variants in NRXN1 and HTR2A

Chr:pos	Ref	Alt	rsID	OCD allele freq.	Ctrl allele freq.	ExAC allele freq.	Amino acid change	Candidate variant from sequencing
NRXN1
chr2:50149133	C	T	rs113380721	0.0019	0.0030	0.0033	Syn	No
chr2:50149214	A	G	rs112536447	0.0001	0.0010	0.0003	Syn	No
chr2:50280604	T	C	rs79970751	0.0088	0.0070	0.0058	Syn	No
chr2:50463984	G	A	rs147580960	0.0009	0.0006	0	Syn	Yes
chr2:50464065	C	T	rs80094872	0.0009	0.0003	0^a	Syn	Yes
chr2:50699479	G	A	rs75275592	0.0009	0.0013	0.0010	Syn	No
chr2:50723068	G	A	rs56402642	0.0034	0.0001	0.0018	Syn	Yes
chr2:50724642	A	G	none	0.0009	0	0	I>T	Yes
chr2:50724745	G	T	rs201818223	0.0017	0.0009	0.0011	L>M	Yes
chr2:50733745	G	C	rs147984237	0.0017	0	1.5 × 10⁻⁵	Syn	Yes
chr2:50765412	G	T	rs56086732	0.0089	0.0028	0.0056	L>I	Yes
chr2:50765589	T	C	rs200074974	0.0016	0	0.0011	I>V	Yes
chr2:50779791	C	T	None	0.0008	0	0^a	A>T	Yes
chr2:50779943	T	C	None	0.0009	0	0^a	N>S	Yes
chr2:50847195	G	A	rs78540316	0.0077	0.0036	0.0043	P>S	Yes
chr2:50850686	G	A	rs2303298	0.0107	0.0013	0.0038	Syn	Yes
HTR2A
chr13:47409048	G	A	rs6308	0.0036	0.0012	0.0023	A>V	Yes
chr13:47409701	G	A	rs141413930	0.0020	0.0012	0.0026^a	Syn	Yes
chr13:47409149	T	A	rs35224115	0.0019	0.0047	0.0044	Syn	No
chr13:47466622	G	A	rs6305	0.0386	0.0225	0.027^b	Syn	Yes

ExAC allele freq. shown for NFE population
^aExcluded from ExAC analysis because of low-confidence call from pooled sequencing
^bExcluded from ExAC analysis because of frequency >0.01

Quick links

Search