Fig. 4 | Nature Communications

Fig. 4

From: Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm

Fig. 4

Fast in vivo brain imaging with Er-RENPs@PMH-PEG in the NIR-IIb region. a Color photograph of a C57Bl/6 mouse (with hair shaved off) preceding NIR-IIb fluorescence imaging. b–d Time-course NIR-IIb brain fluorescence images (exposure time: 20 ms) showing the perfusion of RENPs into various cerebral vessels. The blood-flow velocities of cerebral vessels are given in c (scale bar corresponds to b–d: 2 mm). e, f Cerebral vascular image (exposure time: 20 ms) in NIR-IIb region with corresponding PCA overlaid image f showing arterial (red) and venous (blue) vessels. g SBR analysis of NIR-IIb cerebrovascular image d by plotting the cross-sectional intensity profiles

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