Fig. 1 | Nature Communications

Fig. 1

From: Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme

Fig. 1

Structure of AAT with α-methylaspartate. The PLP cofactor in the external aldimine (chain A in light green) and the internal aldimine (chain B in dark green) forms are shown in yellow and gray carbon scheme, respectively. In the external aldimine, R292 and R386 interact directly with the carboxylate groups of α-methylaspartate. These interactions are not present in the internal aldimine. Here and in Figs. 2, 3, and 5, the deuterium atoms are colored green and the external aldimine is labeled as PLA

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