Fig. 5
From: Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme

Extended hydrogen bond network near N1-PLP in the internal aldimine a and external aldimine b. c Proposed Grotthüss proton hopping mechanism, leading to the protonation of H189 during the formation of the external aldimine. For clarity, the omit |F o|−|F c| difference nuclear scattering maps are presented for deuterium atoms on His residues