Fig. 4
From: Gene isoforms as expression-based biomarkers predictive of drug response in vitro

Pan-cancer validation of candidate biomarkers. Consistency between the training sets (CCLE and GDSC) and the validation set (gCSI) at the level of a, b drug sensitivity and c isoform and gene expression values. a The area above the drug response curve (AAC) values between the two training datasets and gCSI are plotted with their correlations for the common drugs. b The distributions of the AAC values compared for each and dataset. c The distribution of Pearson correlations for candidate biomarker expressions between CCLE and gCSI plotted for each common drug. d The number of candidate and pre-validated biomarkers plotted for each drug