Table 3 Risk estimates for the identified food allergy loci dependent on the eczema status

From: Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy

SNP ID

Chr

Cases (n)

Controls (n)

EA

AA

OR

95% CI

P value

Food allergy, no eczema

rs12123821

1

152

3373

T

C

1.77

1.15–2.74

9.4 × 10−3

rs11949166

5

152

3373

A

T

1.61

1.27–2.04

8.9 × 10−5

rs9273440

6

71 (PN)

3373

T

C

1.67

1.19–2.35

3.2 × 10−3

rs2212434

11

152

3373

T

C

1.14

0.90–1.44

0.29

rs12964116

18

152

3373

G

A

2.26

1.49–3.43

1.3 × 10−4

Food allergy plus eczema

rs12123821

1

717

3373

T

C

2.13

1.74–2.62

5.6 × 10−15

rs11949166

5

717

3373

A

T

1.69

1.50–1.91

2.4 × 10−17

rs9273440

6

265 (PN)

3373

T

C

1.64

1.36–1.97

2.0 × 10−7

rs2212434

11

717

3373

T

C

1.40

1.25–1.58

1.9 × 10−8

rs12964116

18

717

3373

G

A

1.78

1.41–2.25

1.2 × 10−6

  1. AA alternative allele, AF effect allele frequency, CI confidence interval, EA effect allele, OR odds ratio, PN peanut allergy