Fig. 6
From: Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells
Inter-individual variability of organelle proteome alternations induced by T21. a High correlation of organelle proteome regulation trends between twins and unrelated samples. b The correlation between log2 T1DS/T2N ratios for each organelle and the inter-individual variability of T21/normal FC using unrelated samples. ER, endoplasmic reticulum. c The distribution of T21/normal ratios of mitochondrial proteins and other proteins in the proteome, for twin samples and unrelated individuals. d The distribution of T21/normal ratios of cytosolic ribosome proteins (Cyto_Ribo), mitochondrial ribosome proteins (Mito_Ribo), and other proteins in the proteome, for twin samples and unrelated individuals
