Fig. 3

Accessory genome analysis. a Hierarchical clustering based on pairwise Jaccard distances, the distribution of hosts in the two main groups is presented as pie charts. The vertical color strip shows the correspondence of the accessory genome groups with the BAPS clusters identified with the core genome. The presence of virulence genes is shown as heatmap blocks whose opacity is proportional to the copy number. b Discriminant analysis of principal components (DAPC) showing the complete separation between bovine and human lineages based on the accessory genome. c Boxplots showing the abundance of virulence genes (gray) and all the accessory genes (black) in bovine and human lineages