Fig. 3
From: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
Significant effects of individual baldness loci and enriched pathways on disease or mortality risk. Arcs between the loci and the pathways indicate the membership of the genes in that locus in that pathway. The colour and the numbers represent the z-scores from the regressions. Only significant results (q value <0.05) have been reported. Although in several cases, the pathway effects seem to be mainly driven by specific loci, in most cases the overall effect is greater than that of any individual locus. Moreover, we can see examples of pathway-specific effects not attributable to any specific locus, for example, the effect of WNT ligand biogenesis and Class B/2 (Secretin family receptors) pathways on height is detected only at the pathway level and is in the opposite direction to the overall polygenic score and those of the individual loci
