Fig. 3
From: Structural insights into DNA cleavage activation of CRISPR-Cas9 system
The EM-based atomic model of the ternary complex. a The EM density-based atomic model with the 41-bp DNA target (in cartoon). The possible positions of two DNA strands of the PAM distal end are indicated by two arrows. b The close contacts of the HNH domain with the REC1 and PI domains. c Three rotational states of the HNH domain. d Different state distances from the Cα atom of the catalytic residue 840 to the phosphorus of the scissile bond
