Table 2 Ni-catalyzed cross-coupling of unactivated alkylzincs 1 with 2a a

From: Highly selective nickel-catalyzed gem-difluoropropargylation of unactivated alkylzinc reagents

 
  1. Bn, benzyl
  2. aReaction conditions (unless otherwise specified): 1 (1.2 equiv in 2 mL DMA), 2a (0.6 mmol, 1.0 equiv), dioxane (4 mL) for 8 h
  3. b5 mol% of NiCl2 was used
  4. cReaction run in 0.3 mmol scale and 1.5 equiv of 1o was used
  5. d0.5 mol% of Ni(dppf)Cl2 and 0.5 mol% of tpy were used
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