Fig. 1 | Nature Communications

Fig. 1

From: Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci

Fig. 1

Study design. Flowchart illustrating the three separate analyses performed then collated to find consistent significant (p < 1.85 × 10−8, linear model, linear mixed model, see ‘Methods’) and directional changes in risk haplotype-specific DNA methylation (HSM) peaks. The three data sets comprise: 1DISC (n = 895), 2FOLL (n = 1343) and 3REPL (n = 890)

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