Fig. 3

Expression of Stim1 mRNA is downregulated in 3d/3d spleen cells. Histograms show a the absolute gene expression difference between 3d/3d and WT mice for proteins involved in endolysosomal maturation and antigen presentation and b the relative fold changes in gene expression in 3d/3d vs. WT splenocytes (genes upregulated are shown in red and downregulated in blue)