Table 1 List of Aspergillus oryzae strains generated

From: Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives

Aspergillus oryzae strain

Heterologous genes from C. passeckerianus

Compounds produced de novo

Reference

GC

Pl-ggs, Pl-cyc

2

 

GCP1

Pl-ggs, Pl-cyc, Pl-p450-1

3

 

GCP1P2

Pl-ggs, Pl-cyc, Pl-p450-1, Pl-p450-2

4

This work

GCP1P2S

Pl-ggs, Pl-cyc, Pl-p450-1, Pl-p450-2, Pl-sdr

5

 

GCP1P2SA

Pl-ggs, Pl-cyc, Pl-p450-1, Pl-p450-2, Pl-sdr, Pl-atf

6

 

NSAR1 7

Pl-ggs, Pl-cyc, Pl-p450-1, Pl-p450-2, Pl-sdr, Pl-atf, Pl-p450-3

1, 6

Bailey et al.27

  1. The C. passeckerianus genes expressed heterologously in these strains are reported, as well as related compounds produced de novo
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