Fig. 2
Enrichment in the BL-Hi-C method. a The percentage of PETs that are consistent with public CTCF- and RNAPII-binding sites for BL-Hi-C (blue), in situ Hi-C (purple), and HiChIP (green). b The percentage of PETs that are consistent with ChromHMM-annotated DNA elements for BL-Hi-C (blue), in situ Hi-C (purple), and HiChIP (green). The enrichment patterns are indicated by comparing the public ChIP-seq data of CTCF (pink), RNAPII (orange), and the control (light yellow). The P-value is calculated by comparing BL-Hi-C to in situ Hi-C and HiChIP (two-sided t-test, **P < 0.01, ***P < 0.001, error bar, s.e.m.). c The relative fold enrichment of BL-Hi-C PETs at transcription factor-binding sites. The x-axis represents the percentage of BL-Hi-C PET counts. The y-axis represents the PET count ratio between BL-Hi-C and in situ Hi-C (Rao et al.) at each TF-binding site. d The classification of public CTCF peaks into high, normal, and low for fold changes of > 1, from −1 to 1, and < −1, respectively, between BL-Hi-C and in situ Hi-C (Rao et al.). The y-axis refers to the counts of CTCF peaks for each group. e The enrichment of high (blue), normal (green), and low (pink) grouped CTCF peaks at genomic features, according to the homer results
