Fig. 3
From: Structural basis for the assembly of the Ragulator-Rag GTPase complex
The overall structure of Ragulator in complex with RagA(RD)-C(RD). a Ribbon model representation of the crystal structure of the Ragulator-RagA(RD)-C(RD) complex. p18, magenta; p14, yellow; MP1, red; p10, green; HBXIP, blue; RagA(RD), cyan; RagC(RD), orange; N, amino terminus; C, carboxyl terminus. The locations of helices α1, α2, α3, and α4 helices, and the M-loop and C-terminal tail of p18, are shown (upper panel). The structure is viewed from two different angles rotated at 90° along the horizontal axis (lower panel). b Surface representation of Ragulator-RagA(RD)-C(RD) (upper panel). The structure is viewed from two different angles rotated at 90° along the horizontal axis (lower panel). c Orientations of roadblock heterodimers upon formation of the heterotetramer in the structure of Ragulator (left panel) and Ragulator-RagA(RD)-C(RD) (right panel). d Schematic model of the structure of the Ragulator-RagA(RD)-C(RD) complex
