Fig. 2
Mitochondrial and histone stress increase the expression of chromatin remodelers. a Volcano plots depicting changes in gene expression measured by RNA sequencing after treatment with cco-1 or his-3 RNAi. Chromatin remodelers24 are highlighted in the plots. The order of chromatin remodelers on the right is based on adjusted P-value. b, c The expression of chromatin remodelers measured by qRT-PCR after treatment with b cco-1 or c his-3 RNAi. In b and c, N2 worms were collected for qRT-PCR analysis at L4 stage. Bars represent mRNA levels relative to empty vector with error bars indicating mean ± s.d. of three biological replicates, each with three technical replicates (*P < 0.05, **P < 0.01; unpaired Student’s t-test)
