Fig. 6

ISW-1 is required for mitochondria- and histone-mediated longevity. a N2 and isw-1(n3297) mutant lifespan on cco-1 RNAi. b N2 lifespan on combined isw-1 and cco-1 RNAi according to RNAi regimen ii (see Fig. 3a). c N2 lifespan on his-3 RNAi. d isw-1(n3297) mutant lifespan on his-3 RNAi. e N2 lifespan on combined cco-1 and his-3 RNAi. See Supplementary Table 2 for lifespan statistics. f Model based on data presented here