Fig. 2
From: Highly enantioselective catalytic synthesis of chiral pyridines

Practical aspects of CA to alkenyl pyridines and functionalisation of chiral pyridine products. a Scaling up, raising the reaction temperature, as well as use of recovered Cu-catalyst, are well tolerated by the present catalytic system. b The presence of a reactive substituent on the pyridine ring allowed the addition products to be further functionalised