Fig. 3
From: Highly enantioselective catalytic synthesis of chiral pyridines
Cu-catalysed CA to substrates 12 and proposed catalytic cycle. a These experiments clarify the difference in reactivity between 4-substituted and 2-substituted pyridines. b Proposed tentative catalytic cycle for LA promoted Cu-catalysed CA of Grignard reagents to alkenyl pyridines 1a
