Fig. 4

Synaptic inputs to OFF OS RGCs. a Current evoked in an OFF OS RGC by a light step (200 μm diameter) from darkness measured across a range of holding voltages. Yellow rectangle indicates light stimulus. b IV relationship for the stimulus in a. Error bars indicate SEM across n = 13 cells. Peak currents were measured in the temporal window (0–200 ms) indicated by red rectangle in a. c Current evoked in an OFF OS RGC by a light step (1200 μm diameter) from darkness measured across a range of holding voltages. Yellow rectangle indicates light stimulus. d IV relationship for the stimulus in c. Error bars indicate SEM across n = 13 cells. Peak currents were measured in the temporal window (500–1000 ms) indicated by blue rectangle in c. e Peak currents at excitatory reversal potential (red trace) and chloride reversal potential (blue trace) to spots of varying diameters for n = 13 cells. Currents were measured in a 0–200 ms temporal window at E _cat and 500–1000 ms temporal window at E _Cl. Shaded regions indicate SEM across cells. f Absolute peak currents evoked by a 200 μm diameter spot of light in OFF OS RGCs. Dotted line indicates peak baseline noise level. Note logarithmic scale