Fig. 5
From: Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor
In vitro evaluation of KUNB31. a Anti-proliferation values of 6a in immortalized cancerous (NCI-H23, UC3, HT29) and noncancerous (HEK-293) cells. b Representative Western blot analyses 24h after treatment with 6a in HT29 cells at concentrations of 1, 3, 5, 15 and 30 μM. Negative and positive controls include DMSO (D) and geldanamycin (G) at 500 nM, respectively
