Fig. 6
Real-time fluorescence imaging of adsorption at drug crystal surfaces over 120 s following treatment with aqueous NP1-P188 (fluorescence shown in white for clarity) and NP1-P188 labelling of natural fibre surfaces. a Naproxen (Supplementary Movie 1). b Ibuprofen (Supplementary Movie 2). c Paclitaxel (Supplementary Movie 3). Scale bars = 10 μm. See Supplementary Fig. 7 for alternative views showing images as red fluorescence overlaid on the differential interference contrast (DIC) images and Supplementary Movies 4–6. d Plot of increasing drug crystal surface fluorescence over time for the fields of view shown; naproxin (circles), ibuprofen (squares), paclitaxel (triangles). e Plot of fluorescence stability of adsorbed 1/P188 on naproxen crystal surface in water over 50 min. Individual crystal shown at 20, 30, 40, 50 min (Supplementary Movie 13). f Fluorescence image following treatment of human hair with NP1-P188, scale bar = 250 μm. g Fluorescence images following treatment of feather with NP1-P188, scale bar = 250 μm. P188 negative controls (Supplementary Fig. 11)
