Fig. 1
From: Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
Upregulated Gal-3 levels in mice during experimental C. neoformans infection. C57BL/6 mice were intratracheally infected with H99 yeast cells (red line with circle) or PBS (blue line with square) and Gal-3 levels were verified in tissues and serum during the course of C. neoformans infection. On days 3, 7, and 14 after the fungal inoculation, samples collected of brain (a), spleen (b), lungs (c), and serum (d), were homogenized and assessed by ELISA regarding the Gal-3 concentration. Gal-3 levels were upregulated over time after infection with C. neoformans. Bars represent the mean ± SD of Gal-3 levels obtained from triplicate samples in groups of five animals. Statistically significant differences are denoted by asterisks (*p < 0.05, **p < 0.005, unpaired Student’s t-test)
