Fig. 6 | Nature Communications

Fig. 6

From: RETRACTED ARTICLE: REST regulates the cell cycle for cardiac development and regeneration

Fig. 6

Co-upregulation of REST and cardiomyocyte proliferation in injured neonatal hearts. a, b Quantitative immunofluorescence (a Scale bar = 40 μm.) and scatter plot b showing increased expression of REST and its positive relation with the expression of cell cycle markers in cardiomyocytes. Average counts from six fields/section, four sections/ventricle, four ventricles/stage at P7, P14, and P28, mean ± s.d. *p < 0.05 by one-way ANOVA followed by Tukey’s test. APB/APR apex border/apex remote. c Co-immunofluorescence showing consistently ~60% of EdU+ cells express REST (arrow) in regenerating neonatal hearts. Scale bar = 10 μm. Data are presented as mean ± s.d. (n = 4/stage)

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