Fig. 5 | Nature Communications

Fig. 5

From: Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction

Fig. 5

Antigen exchange following vaccinia infection requires both BatF3 and Ccr7. a Schematic of experimental design. b WT, BatF3 −/−, and Ccr7 −/− mice were infected with vaccinia-ova and 2 weeks later violet proliferation dye (VPD)-labeled OT1 T cells were transferred. OT1 division was evaluated (Supplementary Fig. 3). c Quantification of the percent divided in the groups shown in b, where mice of each genotype were pooled from three independent experiments of three mice each. Statistical analysis was done using an unpaired t-test where the p-value between wild type and BatF3 −/− is <0.0001 or wild type and CCR7−/− is <0.0001. Error bars are mean ± standard error of the mean

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