Fig. 1
From: Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase
Domain organization of Bcr-Abl. The two isoforms of the fusion protein Bcr-Abl, p210, and p190, are shown with their sizes and domain arrangement. The breakpoint between Bcr and Abl is indicated with a dotted line. CC coiled-coil, DH Dbl-homology, PH Pleckstrin-homology, SH3/SH2 Src-homology 3/2, FABD F-actin binding domain
