Fig. 7
From: Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase
Model of the structural organization of Bcr-Abl p210 and contributions to cellular localization and signaling. Domain CC coiled-coil, DH Dbl-homology, PH Pleckstrin-homology, SH3/SH2 Src-homology 3/2, FABD F-actin binding domain. High-resolution structures of the individual domains were solved in this study (DH: PDB ID 5NR6, PH: PDB ID 5OC7) and in previous studies (CC: PDB ID 1K1F, SH3: PDB ID 1OPK, SH2-Kinase: PDB ID 1OPL chain B, FABD: 1ZZP)
