Fig. 1
From: Generic wound signals initiate regeneration in missing-tissue contexts
Two hypotheses for generating regeneration initiation signals. Hypothesis I: regeneration-initiation signals are induced exclusively after R-wounds, such as amputations; H-wounds, such as incisions or other epidermal wounds, activate different signals leading to wound healing but not to a subsequent regenerative response. Hypothesis II: the same signals are induced generically after all types of injuries; the tissue contexts in which the signals are induced determine whether regeneration occurs
