Fig. 6
From: Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling
miRNA modulation can enhance MSC differentiation in 3D hydrogels. a Phase contrast images of encapsulated hMSCs (black and white) on D14. Scale bar, 20 μm. b 3D projections of hydroxyapatite staining (green) after 14 days encapsulation in 3D hydrogels. c Quantitation of hydroxyapatite levels. Data is shown as mean Osteoimage intensity relative to Hoechst intensity ± SD for N = 9 gels across 3 hMSC donors. Samples were analysed by one-way ANOVA with Tukey post hoc testing. Statistically different samples are denoted by *p < 0.05, **p < 0.01 and ***p < 0.001
