Fig. 3 | Nature Communications

Fig. 3

From: Yolk sac macrophage progenitors traffic to the embryo during defined stages of development

Fig. 3

Trafficking is associated with cellular morphology. Intravital spinning disc microscopy of YS vasculature in E10.5 Cx3cr1Cre:Rosa26mT/mG embryos. a Schematic graph for the Cx3cr1Cre:Rosa26mT/mG mouse model. b Image series of CX3CR1 GFP+ (green) YS pre-macrophages; direction of flow from top to bottom (from Supplementary Movie 7). cf Dendrite-shaped CX3CR1 GFP+ macrophages (green) with intravascular protrusions (c, d) further illustrated by multiplanar reconstructions in XY (e, from Supplementary Movie 8) and orthogonal YZ views including heat map (f); endothelium (mTomato, red). Scale bars are 20 µm (b, c, e), 10 µm (d)

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