Fig. 3 | Nature Communications

Fig. 3

From: Dysbindin links presynaptic proteasome function to homeostatic recruitment of low release probability vesicles

Fig. 3

Presynaptic overexpression of the mutant proteasome subunit DTS does not induce apparent changes in synapse morphology. a Immunostainings of a control NMJ (elavC155-Gal4) and an NMJ expressing two copies of the mutant proteasome subunit DTS5 presynaptically (elavC155-Gal4;UAS-DTS5; ‘DTSpre’). Larvae were kept at the permissive temperature (25 °C) throughout development. NMJs were stained for neuronal membrane (aHRP), postsynaptic reticulum (aDLG) and the active zone marker Bruchpilot (aBrp); scale bar overview = 20 µm; scale bar inset = 5 µm. b Quantification of NMJ parameters for the two genotypes shown in (a). Presynaptic DTS overexpression does not result in apparent changes in synapse morphology. Mean ± s.e.m.; n = 24 NMJs; Student’s t-test

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