Fig. 8

BOC-Lys(crotonyl)-AMC inhibits deacetylation by HDAC1. A fluorometric in vitro assay showing that HDAC1 efficiently deacetylates the BOC-Lys(acetyl)-AMC substrate alone, but not in the presence of same amounts of BOC-Lys(crotonyl)-AMC. Performed in triplicate, error bars are standard deviation